-
1.发明授权3-aryl-4(3H) quinazolinone CCK antagonists and pharmaceutical formulations thereof 失效（3H）喹唑啉酮CCK拮抗剂及其药物制剂
公开(公告)号：US5196427A
公开(公告)日：1993-03-23
申请号：US763104
申请日：1991-09-20
IPC分类号： C07D403/06
CPC分类号： C07D403/06
摘要： Novel substituted quinazolinones have been found to exhibit specific binding to cholecystokinin (CCK) receptors in the brain and/or peripheral site such as the pancreas and ileum. The quinazolinones are CCK receptor antagonists and find therapeutic application in the treatment of gastrointestinal disorders and central nervous system disorders, and are useful for appetite regulation in mammals. Pharmaceutical formulations for such indications are described.
摘要翻译： 已经发现新的取代喹唑啉酮显示与脑和/或外周部位如胰腺和回肠中的缩胆囊素（CCK）受体的特异性结合。 喹唑啉酮是CCK受体拮抗剂，可用于治疗胃肠道疾病和中枢神经系统疾病，适用于哺乳动物的食欲调节。 描述了用于这种适应症的药物制剂。
-
2.发明授权3-aryl-4(3H)quinazolinone CCK antagonists and pharmaceutical formulations thereof 失效（3H）喹唑啉酮CCK拮抗剂及其药物制剂
公开(公告)号：US5075313A
公开(公告)日：1991-12-24
申请号：US581943
申请日：1990-09-13
IPC分类号： A61K31/505 , A61P1/00 , A61P3/04 , A61P25/00 , C07D209/14 , C07D239/91 , C07D403/06
CPC分类号： C07D403/06
摘要： Novel substituted quinazolinones have been found to exhibit specific binding to cholecystokinin (CCK) receptors in the brain and/or peripheral site such as the pancreas and ileum. The quinazolinones are CCK receptor antagonists and find therapeutic application in the treatment of gastrointestinal disorders and central nervous system disorders, and are useful for appetite regulation in mammals. Pharmaceutical formulations for such indications are described.
-
搜索结果
2 条记录 (耗时 0.018 秒)
