发明授权
- 专利标题： Methods of preparing optically active epoxy alcohol
- 专利标题（中）： 制备光学活性环氧醇的方法
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申请号： US783448申请日： 1991-10-24
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公开(公告)号： US5213975A公开(公告)日： 1993-05-25
- 发明人: Eiichiro Fukusaki , Hiroshi Takahama , Minako Hada , Yasuyuki Kimura , Hiroyuki Yuasa , Yutaka Nakazono , Shuji Senda , Tetsuo Omata
- 申请人： Eiichiro Fukusaki , Hiroshi Takahama , Minako Hada , Yasuyuki Kimura , Hiroyuki Yuasa , Yutaka Nakazono , Shuji Senda , Tetsuo Omata
- 申请人地址： JPX Ibarake
- 专利权人： Nitto Denko Co., Ltd.
- 当前专利权人： Nitto Denko Co., Ltd.
- 当前专利权人地址： JPX Ibarake
- 优先权： JPX2-294486 19901030; JPX3-170625 19910614
- 主分类号： C07D303/14
- IPC分类号： C07D303/14 ; C07D303/16 ; C12P17/02 ; C12P41/00
摘要：
This invention relates to the methods of preparing optically active epoxy alcohol which is caracterized by the steps of adding carboxylic anhydride to racemic epoxy alcohol (formula 1) in the presence of a hydrolase in an organic solvent, esterifying (-)-form of the epoxy alcohol preferentially to be epoxy ester (formula 2), separating optically active epoxy ester (formula 2) from optically active epoxy alcohol (formula 3) to yield optically active epoxy alcohol (formula 4), so that epoxy alcohol (formula 1) in high purity can be obtained easily and safely at ordinary temperature. ##STR1##
公开/授权文献
- US5830005A Modular plug guide plate 公开/授权日：1998-11-03
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