发明授权
- 专利标题： Diagnosing malignant hyperthermia susceptibility by detection of abnormal proteolytic enzyme digestion fragments of the ryanodine receptor
- 专利标题（中）： 通过检测兰诺定受体的异常蛋白水解酶消化片段来诊断恶性高热敏感性
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申请号： US562719申请日： 1990-08-06
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公开(公告)号： US5242801A公开(公告)日： 1993-09-07
- 发明人: Kevin P. Campbell , C. Michael Knudson , Steven D. Kahl , Charles F. Louis , James R. Mickelson
- 申请人： Kevin P. Campbell , C. Michael Knudson , Steven D. Kahl , Charles F. Louis , James R. Mickelson
- 申请人地址： IA Iowa MN Minneapolis
- 专利权人： University of Iowa Research Foundation,Regents of the University of Minnesota
- 当前专利权人： University of Iowa Research Foundation,Regents of the University of Minnesota
- 当前专利权人地址： IA Iowa MN Minneapolis
- 主分类号： C12Q1/37
- IPC分类号： C12Q1/37 ; G01N33/567 ; G01N33/68
摘要：
The present invention relates to a method of diagnosing malignant hyperthermia susceptibility by detecting abnormal ryanodine receptor fragments following proteolytic enzyme digestion of ryanodine receptors isolated from the sarcoplasmic reticulum of mammalian skeletal muscle. The detection of abnormal ryanodine receptor fragments is indicative of malignant hyperthermia susceptibility.
公开/授权文献
- US5788251A Table lift and transporter 公开/授权日：1998-08-04
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