发明授权
US5244894A 2-aminopyrimidine-4-carboxamide derivatives, their preparation and their
use in therapeutics
失效
2-氨基嘧啶-4-羧酰胺衍生物，其制备及其在治疗中的应用
- 专利标题： 2-aminopyrimidine-4-carboxamide derivatives, their preparation and their use in therapeutics
- 专利标题（中）： 2-氨基嘧啶-4-羧酰胺衍生物，其制备及其在治疗中的应用
-
申请号： US904060申请日： 1992-06-26
-
公开(公告)号： US5244894A公开(公告)日： 1993-09-14
- 发明人: Pascal George , Philippe Manoury , Benoit Marabout , Jacques Froissant , Jean-Pierre Merly
- 申请人： Pascal George , Philippe Manoury , Benoit Marabout , Jacques Froissant , Jean-Pierre Merly
- 申请人地址： Paris
- 专利权人： Synthelabo
- 当前专利权人： Synthelabo
- 当前专利权人地址： Paris
- 优先权： FRX9107939 19910627
- 主分类号： A61K31/505
- IPC分类号： A61K31/505 ; A61K31/506 ; A61P13/00 ; A61P13/02 ; A61P13/08 ; A61P15/00 ; C07D239/42 ; C07D239/46 ; C07D295/13 ; C07D401/06 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D405/12
摘要：
Compounds corresponding to the general formula (I) ##STR1## in which n=2 or 3, X=H, F, Cl or OCH.sub.3, R=H or CH.sub.3, R.sub.1 =H or CH.sub.3, R.sub.2 =alkyl, hydroxyalkyl, (hydroxy)(methoxy)alkyl, dimethoxyalkyl, 2-(aminosulphonyl)ethyl, 2-(methylsulphonyl)ethyl, 2-(methylsulphonylamino)ethyl, aminocarbonylmethyl which is optionally substituted by nitrogen, phenylethyl which is optionally substituted, pyrimidinylaminoalkyl or arylcaronylaminoalkyl, or else R.sub.1 and R.sub.2 form, with the nitrogen which carries them, a piperidine, morpholine, thiomorpholine or piperazine ring, optionally substituted by nitrogen. Use in therapeutics.
公开/授权文献
- US6007188A Particle tolerant printhead 公开/授权日：1999-12-28
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