发明授权
US5244901A 4-pyrimidinecarboxamide derivatives, their preparation and their
application in therapy
失效
4-PYRIMIDINECARBOXAMIDE衍生物，其制备及其在治疗中的应用
- 专利标题： 4-pyrimidinecarboxamide derivatives, their preparation and their application in therapy
- 专利标题（中）： 4-PYRIMIDINECARBOXAMIDE衍生物，其制备及其在治疗中的应用
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申请号： US903705申请日： 1992-06-26
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公开(公告)号： US5244901A公开(公告)日： 1993-09-14
- 发明人: Pascal George , Jacques Froissant , Arlette Tixidre
- 申请人： Pascal George , Jacques Froissant , Arlette Tixidre
- 申请人地址： FRX Paris
- 专利权人： Synthelabo
- 当前专利权人： Synthelabo
- 当前专利权人地址： FRX Paris
- 优先权： FRX9107937 19910627
- 主分类号： A61K31/505
- IPC分类号： A61K31/505 ; A61K31/506 ; A61P13/00 ; A61P13/02 ; A61P13/08 ; A61P15/00 ; C07D231/42 ; C07D239/42 ; C07D295/08 ; C07D403/12
摘要：
The present invention provides a compound which is a 4-pyrimidinecarboxamide derivative of general formula (I) ##STR1## in which X represents one or more substituents independently chosen from fluorine, chlorine, methoxy and cyclopropyl,R.sub.1 represents a hydrogen atom or a C.sub.1 -C.sub.3 alkyl group, andR.sub.2 represents a hydrogen atom or a methyl group, or a pharmaceutically acceptable acid addition salt thereof; their preparation and their application in therapy.
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