发明授权
US5278156A 11-beta, 17-alpha, 21-trihydroxy-1, 4-pregnadiene-3, 20 21-[(E-E)-3,7,
11-trimethyl-2,6,10-dodecatrienoate]
失效
11-β，17-α，21-三羟基-1,4-孕二烯-3,201 - [（E-E）-3,7,11-三甲基-2,6,10-十二碳三烯酸酯]
- 专利标题： 11-beta, 17-alpha, 21-trihydroxy-1, 4-pregnadiene-3, 20 21-[(E-E)-3,7, 11-trimethyl-2,6,10-dodecatrienoate]
- 专利标题（中）： 11-β，17-α，21-三羟基-1,4-孕二烯-3,201 - [（E-E）-3,7,11-三甲基-2,6,10-十二碳三烯酸酯]
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申请号： US856858申请日： 1992-03-24
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公开(公告)号： US5278156A公开(公告)日： 1994-01-11
- 发明人: Yutaka Mizushima , Keiko Hoshi , Rie Igarashi , Hirofusa Ajioka , Noriyuki Yamamoto , Masahito Komuro , Koichi Kanehira , Masayuki Inoue , Takashi Nishida , Michio Terasawa , Kenzo Arizono
- 申请人： Yutaka Mizushima , Keiko Hoshi , Rie Igarashi , Hirofusa Ajioka , Noriyuki Yamamoto , Masahito Komuro , Koichi Kanehira , Masayuki Inoue , Takashi Nishida , Michio Terasawa , Kenzo Arizono
- 申请人地址： JPX Okayama JPX Tokyo
- 专利权人： Kuraray Co., Ltd.,Taiho Pharmaceutical Co., Ltd.
- 当前专利权人： Kuraray Co., Ltd.,Taiho Pharmaceutical Co., Ltd.
- 当前专利权人地址： JPX Okayama JPX Tokyo
- 优先权： JPX63-57135 19880309; JPX63-80542 19880331
- 主分类号： C07J5/00
- IPC分类号： C07J5/00 ; A61K31/56
摘要：
11.beta.,17.alpha.,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-[(E,E)-3,7,11-trimethyl-2,6,10-dodecatrienoate] of the formula ##STR1## an antiinflammatory composition thereof and a method for the production thereof.11.beta.,17.alpha.,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-[(E,E)-3,7,11-trimethyl-2,6,10-dodecatrienoate] of the present invention exhibits remarkably excellent antiinflammatory action and besides, displays reduced side effects and can be produced in high selectivity and good yield and conveniently.
公开/授权文献
- US6108602A Vehicle with navigation device 公开/授权日：2000-08-22
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