Unexpectedly large normalized refractive index changes (.DELTA.>10.sup.-5, but possibly even larger than 10.sup.-3) can be obtained in oxide glass, e.g., high-silica glass, by a treatment that comprises exposing at least a portion of the glass at a temperature of at most 250.degree. C. to H.sub.2 or D.sub.2 (partial H.sub.2 or D.sub.2 pressure greater than 1 atmosphere), and irradiating at least a part of the exposed portion with actinic (typically UV) radiation. The method can be used to make optical components that comprise a region (or regions) of raised refractive index, e.g., an in-line refractive index grating in an optical waveguide, a planar optical waveguide, or a phase grating.