发明授权
- 专利标题: Benzylpiperidine compounds and their use
- 专利标题(中): 苄基哌啶化合物及其用途
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申请号: US964851申请日: 1992-12-18
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公开(公告)号: US5294625A公开(公告)日: 1994-03-15
- 发明人: Giichi Goto , Hidefumi Yukimasa , Tetsuji Imamoto
- 申请人: Giichi Goto , Hidefumi Yukimasa , Tetsuji Imamoto
- 申请人地址: JPX Osaka
- 专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX1-6651 19890113; JPX1-179495 19890712; JPX1-253162 19890928
- 主分类号: C12N9/99
- IPC分类号: C12N9/99 ; A61K31/00 ; A61K31/44 ; A61K31/4409 ; A61K31/4418 ; A61K31/445 ; A61K31/4465 ; A61K31/451 ; A61P9/00 ; A61P25/28 ; C07D211/26 ; C07D211/32 ; C07D211/70 ; C07D213/36 ; C07D213/38 ; C07D213/50 ; C07D521/00 ; A61K31/443
摘要:
1. A cyclic amine compound of the formula ##STR1## wherein B means a saturated or unsaturated 5- to 7-membered aza-heterocyclic group which may be substituted; A means a bond or an alkylene or alkenylene group which may be substituted by hydrocarbon residues, oxo, hydroxyimino, and/or hydroxy, --means either a single bond or a double bond (provided that when A means a bond, --means a single bond); R.sub.2 and R.sub.3 independently mean a hydrogen atom or a hydrocarbon residue which may be substituted (provided that both of R.sub.2 and R.sub.3 are not hydrogen atoms) or jointly form a cyclic amino group together with the adjacent nitrogen atom, n is 0, 1 or 2 and p is 1 or 2 or a physiologically acceptable salt thereof.The compounds are useful for therapy of cerebral edema, acute symptoms in cerebral apoplexy and protection of brain and nerve cell, or useful as anticholinesterase or as brain function-improving agent.
公开/授权文献
- US4274997A Halogenated polymers stabilized with triazoles 公开/授权日:1981-06-23
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