发明授权
- 专利标题: 3,4-dehydropiperidine derivatives having psychotropic activity
- 专利标题(中): 具有精神活性的3,4-脱水哌啶衍生物
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申请号: US968267申请日: 1992-10-30
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公开(公告)号: US5296497A公开(公告)日: 1994-03-22
- 发明人: Jan Hartog , Roelof Van Hes , Berend Olivier , Ineke Van Wijngaarden
- 申请人: Jan Hartog , Roelof Van Hes , Berend Olivier , Ineke Van Wijngaarden
- 申请人地址: NLX Weesp
- 专利权人: Duphar International Research B.V.
- 当前专利权人: Duphar International Research B.V.
- 当前专利权人地址: NLX Weesp
- 优先权: NLX8901211 19890516
- 主分类号: C07D211/70
- IPC分类号: C07D211/70 ; C07D405/04 ; C07D405/14 ; C07D409/04 ; C07D411/04 ; C07D413/14 ; C07D417/04 ; C07D417/14 ; A61K31/44
摘要:
The invention relates to 3,4-dehydropiperidine derivatives having psychotropic activity, which compounds are represented by the general formula 1 ##STR1## wherein R is hydrogen or C.sub.1 -C.sub.3 alkyl;R.sub.2 is hydrogen, an unsubstituted or substituted C.sub.1 -C.sub.10 hydrocarbon group, or a group of the general formula ##STR2## wherein A is C.sub.2 -C.sub.10 alkylene,R.sub.5 is hydrogen or C.sub.1 -C.sub.3 alkyl, andR.sub.6 is unsubstituted or substituted aryl or heteroaryl, hydrocarbon, substituted or unsubstituted (hetero)aralkyl, or substituted or unsubstituted heterocyclic; or wherein R.sub.5 and R.sub.6 together with the carbamoyl group to which they are bound constitute a heterocyclic ring system;n has the value 1 or 2; andZ is a heterocyclic group.
公开/授权文献
- US5962961A Thermal field emission electron gun 公开/授权日:1999-10-05
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