发明授权
US5300506A Indolylalkyl derivatives of pyrimidinylpiperazine for treating vascular
headache
失效
用于治疗血管性头痛的嘧啶基哌嗪的吲哚基烷基衍生物
- 专利标题： Indolylalkyl derivatives of pyrimidinylpiperazine for treating vascular headache
- 专利标题（中）： 用于治疗血管性头痛的嘧啶基哌嗪的吲哚基烷基衍生物
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申请号： US960063申请日： 1992-10-13
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公开(公告)号： US5300506A公开(公告)日： 1994-04-05
- 发明人: David W. Smith , Frank D. Yocca , Joseph P. Yevich , Ronald J. Mattson , Andrew Williams , Edward H. Ruediger
- 申请人： David W. Smith , Frank D. Yocca , Joseph P. Yevich , Ronald J. Mattson , Andrew Williams , Edward H. Ruediger
- 申请人地址： NY New York
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： NY New York
- 主分类号： A61K31/505
- IPC分类号： A61K31/505 ; A61K31/40 ; A61P25/04 ; C07D403/02 ; C07D403/12 ; C07D403/14 ; C07D403/00
摘要：
A series of novel indol-3-ylalkyl derivatives of alkoxypyrimidinylpiperazines are disclosed as Formula I. ##STR1## These compounds are intended to be useful agents for alleviation of vascular headache on the basis of their potent affinity and agonist activity at 5-HT1D binding sites.
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