发明授权
US5302730A Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives
失效
制备6,7-二酰基-7-脱乙酰福斯克林衍生物的方法
- 专利标题： Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives
- 专利标题（中）： 制备6,7-二酰基-7-脱乙酰福斯克林衍生物的方法
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申请号： US71616申请日： 1993-06-04
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公开(公告)号： US5302730A公开(公告)日： 1994-04-12
- 发明人: Tochiro Tatee , Akira Shiozawa , Hirotaka Yamamoto , Yuh-ichiro Ichikawa , Aya Narita , Chikara Komuro , Kazuhisa Narita
- 申请人： Tochiro Tatee , Akira Shiozawa , Hirotaka Yamamoto , Yuh-ichiro Ichikawa , Aya Narita , Chikara Komuro , Kazuhisa Narita
- 专利权人： Nippon Kayaku Kk
- 当前专利权人： Nippon Kayaku Kk
- 优先权： JPX62-159638 19870629; JPX62-159639 19870629
- 主分类号： C07D311/92
- IPC分类号： C07D311/92
摘要：
This invention relates to a process for the preparation of a 6,7-diacyl-7-deacetylforskolin derivative represented by the general formula: ##STR1## wherein R.sup.1 and R.sup.2 each stands for an acyl group and R.sup.3 stands for an aliphatic group having 2 to 3 carbon atoms, which comprises eliminating the acyl group at position 1 in a 1,6,7-triacyl-7-deacetylforskolin derivative represented by the general formula: ##STR2## wherein R.sup.1, R.sup.2 and R.sup.3 are as defined above, by solvolysis. The compound of the formula (I) is expected as medicine.
公开/授权文献
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