发明授权
US5310535A Carboxamide modified polyamine chelators and radioactive complexes
thereof for conjugation to antibodies
失效
羧甲酰胺改性的多胺螯合剂及其与抗体缀合的放射性复合物
- 专利标题： Carboxamide modified polyamine chelators and radioactive complexes thereof for conjugation to antibodies
- 专利标题（中）： 羧甲酰胺改性的多胺螯合剂及其与抗体缀合的放射性复合物
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申请号： US874244申请日： 1992-04-24
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公开(公告)号： US5310535A公开(公告)日： 1994-05-10
- 发明人: William J. Kruper, Jr. , William A. Fordyce , A. Dean Sherry
- 申请人： William J. Kruper, Jr. , William A. Fordyce , A. Dean Sherry
- 申请人地址： MI Midland TX Austin
- 专利权人： The Dow Chemical Company,The University of Texas
- 当前专利权人： The Dow Chemical Company,The University of Texas
- 当前专利权人地址： MI Midland TX Austin
- 主分类号： C07D257/02
- IPC分类号： C07D257/02 ; A61K39/44 ; A61K51/00 ; A61K51/04 ; A61K51/10 ; C07B59/00 ; C07F5/00 ; C07K16/00 ; C07K16/30 ; A61K43/00 ; A61K49/02
摘要：
A group of functionalized polyaminocarboxamide modified chelators that form complexes with rare earth-type metal ions are disclosed. The complexes, covalently attached to an antibody or antibody fragment, can be used for therapeutic and/or diagnostic purposes.
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