Invention Grant
- Patent Title: DNA encoding rat and human protein kinase C
- Patent Title (中): 编码大鼠和人类蛋白激酶C的DNA
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Application No.: US945739Application Date: 1992-09-16
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Publication No.: US5324651APublication Date: 1994-06-28
- Inventor: Ono Yoshitaka , Kurokawa Tsutomu , Igarashi Koichi , Nishizuka Yasutomi
- Applicant: Ono Yoshitaka , Kurokawa Tsutomu , Igarashi Koichi , Nishizuka Yasutomi
- Applicant Address: JPX Osaka
- Assignee: Takeda Chemical Industries, Ltd.
- Current Assignee: Takeda Chemical Industries, Ltd.
- Current Assignee Address: JPX Osaka
- Priority: JPX61-149385 19860627; JPX61-217944 19860918; JPX61-281870 19861128; JPX62-40160 19870525
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C12N15/54 ; G01N33/573 ; C12N1/21 ; C12N5/10 ; C12P21/02
Abstract:
Human protein kinase C and rat protein kinase C, recombinant DNA containing DNA sequence coding for kinase C, a transformant transformed with a vector containing the above recombinant DNA, and the production method of human or rat kinase C by cultivating the transformant are disclosed.Kinase C is useful as reagent for studying cellular signal transduction mechanism, as diagnostic and inspection agent for disease, for example tumor, resulting from the trouble of cellular signal transduction mechanism, and as screening agent for a preventive agent or medicine to the disease.
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