发明授权
- 专利标题: Topical composition for preventing or treating acne vulgaris
- 专利标题(中): 预防或治疗寻常痤疮的局部组合物
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申请号: US82855申请日: 1993-06-28
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公开(公告)号: US5344850A公开(公告)日: 1994-09-06
- 发明人: Hamako Hata , Kenya Ishida , Toshiya Sato
- 申请人: Hamako Hata , Kenya Ishida , Toshiya Sato
- 申请人地址: JPX
- 专利权人: Takasago International Corporation
- 当前专利权人: Takasago International Corporation
- 当前专利权人地址: JPX
- 优先权: JPX4-171163 19920629
- 主分类号: A61K8/30
- IPC分类号: A61K8/30 ; A61K8/00 ; A61K8/34 ; A61K9/06 ; A61K9/08 ; A61K31/045 ; A61P17/00 ; A61Q19/00 ; C07C31/125 ; C07C33/02
摘要:
A topical composition for treating or preventing acne vulgaris which comprises at least one saturated or unsaturated chain alcohol having 18 carbon atoms represented by formula (1): ##STR1## wherein a dotted line represents either the presence or the absence of a double bond as an active ingredient, makes it possible to inhibit proliferation of Propionibacterium acnes, which causes acne vulgaris, or kill the bacterium to effectively treat or prevent acne vulgaris. The compound represented by formula (1) can be easily synthesized and has an extremely low toxicity. Furthermore, it exerts an excellent antibacterial effect on Propionibacterium acnes even when used at a relatively low concentration. Thus it can be used only in a small amount , which ensures a high safety.
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