A computerized numerically controlled drilling and milling machine has a worktable 2, 3 for supporting a workpiece 41, one or more tool assemblies 10, 11, 26 for processing the workpiece, and feeding and guiding devices 8, 9; 24, 25; 27, 43 arranged to provide for positioning and simultaneous relative movement between the tool assemblies and the workpiece in a longitudinal as well as a transverse direction. The worktable is in two parts, and the tool assemblies are arranged on the guiding devices in a transversely extending intermediate space 4 between the parts. Further, a clamping and feeding device 30, 44, 27, 43 for the workpiece is provided on each side of the intermediate space for successive alternating feeding of the workpiece.