发明授权
- 专利标题： 2,2-dimethylchromene derivatives, process for their preparation and pharmaceutical compositions in which they are present
- 专利标题（中）： 2,2-二甲基色烯衍生物，其制备方法及其存在的药物组合物
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申请号： US746974申请日： 1991-08-19
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公开(公告)号： US5391751A公开(公告)日： 1995-02-21
- 发明人: Georges Garcia , Alain Di Malta , Patrick Gautier
- 申请人： Georges Garcia , Alain Di Malta , Patrick Gautier
- 专利权人： Garcia; Georges,Di Malta; Alain,Gautier; Patrick
- 当前专利权人： Garcia; Georges,Di Malta; Alain,Gautier; Patrick
- 优先权： FRX8714067 19871012
- 主分类号： A61K31/435
- IPC分类号： A61K31/435 ; A61K31/44 ; A61K31/66 ; A61K31/675 ; A61P9/06 ; A61P9/12 ; C07D405/04 ; C07F9/6558
摘要：
The present invention relates to 2,2-dimethylchromene derivatives of the formula: ##STR1## in which Z represents a halogen atom or a cyano, nitro, acetyl, phosphono or dialkoxyphosohoryl group, the alkoxy group containing 1 to 3 carbon atoms, and the pharmaceutically acceptable salts of the phosphono group.These compounds show an antihypertensive and antiarrythmic activity.The present invention also relates to a process for the preparation of said compounds and to the pharmaceutical compositions in which the are present.
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