发明授权
US5395944A 7-(aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)quinolonecarboxylic and
7-(aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)naphthyridone-carboxylic
acid intermediates
失效
7-（氨基甲基 - 氧杂-7-氮杂 - 双环[3.3.0]辛-7-基）喹啉酮羧酸和7-（氨基甲基 - 氧杂-7-氮杂 - 双环[3.3.0]辛-7-基）萘啶酮 - 羧酸中间体
- 专利标题： 7-(aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)quinolonecarboxylic and 7-(aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)naphthyridone-carboxylic acid intermediates
- 专利标题（中）： 7-（氨基甲基 - 氧杂-7-氮杂 - 双环[3.3.0]辛-7-基）喹啉酮羧酸和7-（氨基甲基 - 氧杂-7-氮杂 - 双环[3.3.0]辛-7-基）萘啶酮 - 羧酸中间体
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申请号： US124129申请日： 1993-09-20
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公开(公告)号： US5395944A公开(公告)日： 1995-03-07
- 发明人: Uwe Petersen , Thomas Schenke , Klaus Grohe , Klaus-Dieter Bremm , Rainer Endermann , Karl G. Metzger
- 申请人： Uwe Petersen , Thomas Schenke , Klaus Grohe , Klaus-Dieter Bremm , Rainer Endermann , Karl G. Metzger
- 申请人地址： DEX Leverkusen
- 专利权人： Bayer Aktiengesellschaft
- 当前专利权人： Bayer Aktiengesellschaft
- 当前专利权人地址： DEX Leverkusen
- 优先权： DEX4232172.7 19920925
- 主分类号： A61K31/47
- IPC分类号： A61K31/47 ; A61K31/435 ; A61K31/4375 ; A61K31/4709 ; A61K31/4741 ; A61P31/04 ; C07D491/04 ; C07D491/048 ; C07D519/00 ; C07D491/044
摘要：
7-(Aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)quinolonecarboxylic acid and 7-(aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)naphthyridonecarboxylic acid derivatives The invention relates to novel derivatives of quinolonecarboxylic acid and naphthyridonecarboxylic acid which are substituted in the 7 position by a 1- (or 5-)aminomethyl-2- (or 3-)oxa-7-aza-bicyclo[3.3.0]oct-7-yl residue, their salts, processes for their preparation and antibacterial agents containing these compounds.
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