发明授权
- 专利标题: Pyridine compounds which have useful pharmaceutical activity
- 专利标题(中): 具有有用药物活性的吡啶化合物
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申请号: US66058申请日: 1993-06-14
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公开(公告)号: US5399575A公开(公告)日: 1995-03-21
- 发明人: Walter-Gunar Friebe , Wolfgang Kampe , Marcel Linssen , Otto-Henning Wilhelms
- 申请人: Walter-Gunar Friebe , Wolfgang Kampe , Marcel Linssen , Otto-Henning Wilhelms
- 申请人地址: DEX Mannheim
- 专利权人: Boehringer Mannheim GmbH
- 当前专利权人: Boehringer Mannheim GmbH
- 当前专利权人地址: DEX Mannheim
- 优先权: DEX4038335.0 19901201
- 主分类号: A61K31/44
- IPC分类号: A61K31/44 ; A61K31/4402 ; A61K31/4406 ; A61K31/4409 ; A61K31/4418 ; A61K31/4427 ; A61P37/08 ; C07D213/30 ; C07D213/55 ; C07D213/56 ; C07D213/57 ; C07D213/89 ; C07D401/04 ; C07D401/10 ; C07D401/12 ; C07D213/54
摘要:
Compounds of the formula I ##STR1## in which A signifies an alkylene radical with 1 to 3 carbon atoms or a group --CH.dbd.CH--, B an oxygen atom or a valency bond, m a whole number from 0 to 5, n the number 0 or 1, X a valency bond, an oxygen atom or a sulphur atom, Y a valency bond or a phenylene radical substituted, if desired, one or more times by C.sub.1 - to C.sub.6 -alkyl, C.sub.1 - to C.sub.6 -alkoxy, halogen, hydroxyl or aminocarbonyl, Z hydrogen, halogen, C.sub.1 - to C.sub.6 -alkyl or cyano and R a group CN, COOH, COOC.sub.1 - to C.sub.6 -alkyl, CONH-tetrazolyl, CON(OH)(C.sub.1 -C.sub.6 -alkyl) or 5-(1H)-tetrazolyl, as well as, for the case that Y represents a phenylene radical, also hydrogen, with the exception of the compound 4-[2-(4)-pyridinovinyl]-carboxymethoxybenzene, their physiologically compatible salts and processes for their preparation, as well as medicaments containing these compounds for the treatment of allergic diseases.
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