发明授权
US5405848A Substituted thiazolylaminotetrahydropyridopyrimidines derivatives useful
as platelet aggregation inhibitors
失效
用作血小板聚集抑制剂的取代的噻唑基氨基四氢吡啶并嘧啶衍生物
- 专利标题： Substituted thiazolylaminotetrahydropyridopyrimidines derivatives useful as platelet aggregation inhibitors
- 专利标题（中）： 用作血小板聚集抑制剂的取代的噻唑基氨基四氢吡啶并嘧啶衍生物
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申请号： US171581申请日： 1993-12-22
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公开(公告)号： US5405848A公开(公告)日： 1995-04-11
- 发明人: Pauline J. Sanfilippo , Mary P. Bonner , James J. McNally
- 申请人： Pauline J. Sanfilippo , Mary P. Bonner , James J. McNally
- 申请人地址： NJ Raritan
- 专利权人： Ortho Pharmaceutical Corporation
- 当前专利权人： Ortho Pharmaceutical Corporation
- 当前专利权人地址： NJ Raritan
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/425 ; C07D413/00 ; C07D471/00
摘要：
This invention relates to substituted thiazolylaminotetrahydropyridopyrimidines derivatives of the following general formula, the substituent groups of which are as defined in the specification herein: ##STR1## These compounds are useful as inhibitors of platelet aggregation and inhibitors of adhesion molecules and may be provided in pharmaceutical compositions and in methods of treating reperfusion thrombosis injury in patients.