发明授权
- 专利标题： DNA's encoding signal peptides
- 专利标题（中）： DNA编码信号肽
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申请号： US311556申请日： 1989-02-16
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公开(公告)号： US5409815A公开(公告)日： 1995-04-25
- 发明人: Yukimitsu Nakagawa , Naofumi Hayasuke , Atsushi Masaki , Yutaka Ishida , Kohji Murakami , Ken Okabayashi , Kiyoshi Tsutsui , Hitoshi Minamino , Kazuo Ikegaya , Kaoru Kobayashi , Haruhide Kawabe , Sadao Ueda
- 申请人： Yukimitsu Nakagawa , Naofumi Hayasuke , Atsushi Masaki , Yutaka Ishida , Kohji Murakami , Ken Okabayashi , Kiyoshi Tsutsui , Hitoshi Minamino , Kazuo Ikegaya , Kaoru Kobayashi , Haruhide Kawabe , Sadao Ueda
- 申请人地址： JPX Osaka
- 专利权人： The Green Cross Corporation
- 当前专利权人： The Green Cross Corporation
- 当前专利权人地址： JPX Osaka
- 优先权： JPX63-33657 19880216
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; C07K7/06 ; C07K7/08 ; C07K14/00 ; C07K14/705 ; C07K14/765 ; C07K19/00 ; C12N1/16 ; C12N15/62 ; C12N15/81 ; C12P21/02 ; C12R1/865 ; C12P21/06 ; C07H21/04
摘要：
Novel signal peptides capable of functioning in yeasts have the amino acid sequence:Met-A.sub.1 -A.sub.2 -X-B-C-D-E-Fwherein A.sub.1 is a peptide chain composed of 1-3 amino acids each selected from the group consisting of Arg, Ser, Lys and His, A.sub.2 is a peptide chain composed of 1-3 amino acids, X is a peptide chain composed of 8-10 hydrophobic amino acids, B is Pro or Ser, C is Gly or Pro, D Cys, Ala, Leu, Ser, Thr and Val, E is Trp or Gln and F is Ala or Gly. DNA sequences coding for these signal peptides can be used for the secretory expression of heterologous proteins in yeasts.
公开/授权文献
- US5599258A Adjustable exercise step and method 公开/授权日：1997-02-04
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