发明授权
- 专利标题: Anilide derivatives
- 专利标题(中): 苯胺衍生物
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申请号: US244998申请日: 1994-06-20
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公开(公告)号: US5416212A公开(公告)日: 1995-05-16
- 发明人: Masakazu Sato , Masahiro Kawase , Akira Manaka , Yutaka Kawashima , Katsuo Hatayama
- 申请人: Masakazu Sato , Masahiro Kawase , Akira Manaka , Yutaka Kawashima , Katsuo Hatayama
- 申请人地址: JPX
- 专利权人: Taisho Pharmaceutical Co., Ltd.
- 当前专利权人: Taisho Pharmaceutical Co., Ltd.
- 当前专利权人地址: JPX
- 优先权: JPX3-343576 19911225
- 主分类号: C07D213/74
- IPC分类号: C07D213/74 ; C07D239/42 ; C07D295/088 ; C07D295/112 ; C07D295/185 ; C07D295/15 ; C07D401/04 ; C07D403/04
摘要:
An anilide compound represented by formula (I): ##STR1## wherein R.sup.1 and R.sup.2, which may be the same or different, each represent an alkyl group having 1 to 4 carbon atoms; n represents 0, 1 or 2; A represents an alkylene group having 1 to 14 carbon atoms or a group represented by --CH.sub.2 CO--; and Ar represents a phenyl group, a phenyl group substituted with a halogen atom, a nitro group, an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, an alkanoyl group having 2 to 5 carbon atoms or a trifluoromethyl group, a benzyl group, a pyridyl group, a pyridyl group substituted with a halogen atom or a trifluoromethyl group, or a pyrimidyl group, or a salt thereof. The disclosed anilide compounds have potent ACAT inhibitory activity.
公开/授权文献
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