发明授权
- 专利标题: Dihydrochalcone derivatives which are hypoglycemic agents
- 专利标题(中): 二氢查耳酮衍生物,它们是降糖药
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申请号: US149912申请日: 1993-11-10
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公开(公告)号: US5424406A公开(公告)日: 1995-06-13
- 发明人: Kenji Tsujihara , Mitsuya Hongu , Nobuyuki Funami , Masanori Inamasu , Kenji Arakawa
- 申请人: Kenji Tsujihara , Mitsuya Hongu , Nobuyuki Funami , Masanori Inamasu , Kenji Arakawa
- 申请人地址: JPX Osaka
- 专利权人: Tanabe Seiyaku Co., Ltd.
- 当前专利权人: Tanabe Seiyaku Co., Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX4-301485 19921112; JPX5-028770 19930218; JPX5-035988 19930225
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; A61K31/7056 ; C07H15/203 ; C07H7/04 ; C07H15/04
摘要:
A method for treatment of diabetes, which comprises administering to a patient with diabetes an effective amount of a dihydrochalcone derivative of the formula: ##STR1## wherein Ar is an aryl group, R.sup.1 is a hydrogen atom or an acyl group, R.sup.2 is a hydrogen atom, an acyl group or .alpha.-D-glucopyranosyl group, or R.sup.1 and R.sup.2 may combine together to form a substituted methylene group, R.sup.3 and R.sup.4 are each a hydrogen atom or an acyl group, OR.sup.5 is a protected or unprotected hydroxy group or a lower alkoxy group; or a pharmaceutically acceptable salt thereof.
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