发明授权
- 专利标题: Orally active renin inhibitors
- 专利标题(中): 口服活性肾素抑制剂
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申请号: US28038申请日: 1993-03-08
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公开(公告)号: US5442044A公开(公告)日: 1995-08-15
- 发明人: Dennis J. Hoover , Bruce A. Lefker , Robert L. Rosati
- 申请人: Dennis J. Hoover , Bruce A. Lefker , Robert L. Rosati
- 申请人地址: NY New York
- 专利权人: Pfizer Inc.
- 当前专利权人: Pfizer Inc.
- 当前专利权人地址: NY New York
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07D211/58 ; C07D401/12 ; C07D409/12 ; C07D417/12 ; C07K5/02 ; C07K5/065 ; C07K5/06 ; A61K38/05
摘要:
This invention relates to compounds of the formula ##STR1## wherein Q, Z, D, E, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are defined as below, and the pharmaceutically acceptable salts thereof are disclosed. The compounds are useful as antihypertensive agents.
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