发明授权
US5445971A Magnetically assisted binding assays using magnetically labeled binding
members
失效
使用磁性标记的结合成员的磁辅助结合测定
- 专利标题： Magnetically assisted binding assays using magnetically labeled binding members
- 专利标题（中）： 使用磁性标记的结合成员的磁辅助结合测定
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申请号： US348780申请日： 1994-12-01
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公开(公告)号： US5445971A公开(公告)日： 1995-08-29
- 发明人: Thomas E. Rohr
- 申请人： Thomas E. Rohr
- 申请人地址： IL Abbott Park
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： IL Abbott Park
- 主分类号： G01N33/543
- IPC分类号： G01N33/543 ; G01N33/546 ; G01N33/553
摘要：
The present invention provides devices for performing binding assays. Such devices comprise (i) a reaction vessel where unbound and immobilized magnetically-labeled reagent are produced in relation to the amount of said analyte in said test sample; (ii) a separation means for partitioning said immobilized magnetically-labeled reagent and said bound magnetically-labeled reagent; (iii) a magnetic field generator means for the application of a magnetic field to said magnetically-labeled reagent; and (iv) a measurement means to assess the effect of said magnetic field on said magnetically-labeled reagent as a measure of the presence or amount of said analyte in said test sample. The device provided by the instant invention can run, for example, direct indirect, competitive, inhibition and sandwich assay formats.
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