发明授权
US5457133A R-enantiomers of N-propargyl-aminoindan compounds, their preparation and
pharmaceutical compositions containing them
失效
N-炔丙基 - 氨基茚满化合物的R-对映异构体，其制备方法和含有它们的药物组合物
- 专利标题： R-enantiomers of N-propargyl-aminoindan compounds, their preparation and pharmaceutical compositions containing them
- 专利标题（中）： N-炔丙基 - 氨基茚满化合物的R-对映异构体，其制备方法和含有它们的药物组合物
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申请号： US198205申请日： 1994-02-17
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公开(公告)号： US5457133A公开(公告)日： 1995-10-10
- 发明人: Moussa B. H. Youdim , John P. M. Finberg , Ruth Levy , Jeffrey Sterling , David Lerner , Tirtsah Berger-Paskin , Haim Yellin
- 申请人： Moussa B. H. Youdim , John P. M. Finberg , Ruth Levy , Jeffrey Sterling , David Lerner , Tirtsah Berger-Paskin , Haim Yellin
- 申请人地址： ILX Jerusalem ILX Haifa
- 专利权人： Teva Pharmaceutical Industries Ltd.,Technion Research and Development Foundation Ltd.
- 当前专利权人： Teva Pharmaceutical Industries Ltd.,Technion Research and Development Foundation Ltd.
- 当前专利权人地址： ILX Jerusalem ILX Haifa
- 优先权： ILX92952 19900103
- 主分类号： C07C211/38
- IPC分类号： C07C211/38 ; A61K31/00 ; A61K31/13 ; A61K31/135 ; A61K31/195 ; A61K31/215 ; A61K45/06 ; A61P25/00 ; A61P25/16 ; A61P25/24 ; A61P25/28 ; C07C209/88 ; C07C211/30 ; C07C211/42 ; C12N9/99
摘要：
R(+)-N-propargyl-1-aminoindan, its preparation and use and pharmaceutical compositions containing it. The novel compound was found to be useful for the treatment of human patients for Parkinson's disease, memory disorders, dementia of the Alzheimer type (DAT), depression and the hyperactive syndrome.
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