Shock dampening hitch ball assembly
    1.
    发明授权
    Shock dampening hitch ball assembly 有权
    冲击阻尼联结球总成

    公开(公告)号:US07976054B1

    公开(公告)日:2011-07-12

    申请号:US12151428

    申请日:2008-05-05

    IPC分类号: B60D1/06

    CPC分类号: B60D1/06 B60D1/50

    摘要: A hitch ball assembly attenuates the lateral forces experienced by a trailer while being towed by a tractor. A ball assembly has a flange with a neck extending upwardly therefrom and a hitch ball seated atop the neck. A wedge, having a pair of linear points, extends downwardly from the flange as does a threaded shank that passes through the wedge, the points being located on either side of the shank. The ball assembly is attached to a draw bar attached mount arm such that the shank passes through a bore in the mount arm with the points of the wedge seated within slots on an upper surface of the mount arm. A resilient bushing is received on the shank and abuts a lower surface of the mount arm, while a plate abuts the bushing, each held thereat by a locking nut threadably attached to an end of the shank.

    摘要翻译: 拖车组件通过拖拉机拖拉时,可以减轻拖车遇到的横向力。 球组件具有凸缘,颈部由颈部向上延伸,并且搭接球位于颈部顶部。 具有一对直线点的楔形物从法兰向下延伸,并且穿过楔形物的螺纹柄部分,该点位于柄的任一侧上。 球组件附接到拉杆附接的安装臂,使得柄穿过安装臂中的孔,楔的点位于安装臂的上表面上的槽内。 弹性衬套容纳在柄上并且邻接安装臂的下表面,同时板抵靠衬套,每个衬套通过螺纹连接到柄的端部的锁定螺母来保持。

    Power plant with motorless feed pump
    2.
    发明申请
    Power plant with motorless feed pump 审中-公开
    带电动供料泵的发电厂

    公开(公告)号:US20070095079A1

    公开(公告)日:2007-05-03

    申请号:US11265013

    申请日:2005-11-03

    申请人: Jeffrey Sterling

    发明人: Jeffrey Sterling

    CPC分类号: F25B1/08

    摘要: The present invention relates to a novel method for operating a thermal power plant or refrigeration cycle in which a spent low pressure working fluid is recycled to a high pressure vaporizer using temperature control within a heat exchanger instead of employing a working fluid feed pump. While the non-steady process is similar to a Rankine cycle, technically, it is no longer a Rankine cycle.

    摘要翻译: 本发明涉及一种用于操作热电厂或制冷循环的新方法,其中废热的低压工作流体使用热交换器内的温度控制再循环至高压蒸发器,而不是使用工作流体供给泵。 虽然不稳定的过程类似于兰金循环,但在技术上,它不再是兰金循环。

    Indanylamino uracils and their use as antioxidants and neuroprotectants
    3.
    发明申请
    Indanylamino uracils and their use as antioxidants and neuroprotectants 审中-公开
    茚基氨基尿嘧啶及其作为抗氧化剂和神经保护剂的用途

    公开(公告)号:US20070021450A1

    公开(公告)日:2007-01-25

    申请号:US11182452

    申请日:2005-07-15

    IPC分类号: A61K31/513 C07D239/545

    CPC分类号: C07D239/545

    摘要: Disclosed are compounds having the structure: wherein, R1 is H, NH2, NH—(C1-C4)alkyl, or N—[(C1-C4)alkyl]2; R2 and R3 are each independently H, (C1-C4)alkyl, or wherein R4 is H, (C1-C4)alkyl, halogen, hydroxy, (C1-C10)alkoxy, cyano, nitro, —NR5R6, or —OCONR7R8; wherein R5 and R6 are each independently H, or a substituted or unsubstituted (C1-C4)alkyl; and wherein R7 and R8 are each independently H, or substituted or unsubstituted (C1-C4)alkyl, or (C1-C10)aryl; and wherein only one of R2 and R3 is H, enantiomers, tautomers, and pharmaceutically acceptable salts of the compounds, pharmaceutical compositions containing such compounds or salts, and processes for their preparation. The subject invention also provides methods of alleviating symptoms of neurologic and inflammatory disorders, methods of preventing oxidation of lipids, proteins, or deoxyribonucleic acids on a cellular level, and methods of protecting human red blood cells from lysis by O2 radicals.

    摘要翻译: 公开了具有以下结构的化合物:其中R 1是H,NH 2,NH-(C 1 -C 4) 或N - [(C 1 -C 4)烷基]亚烷基;或N - [(C 1 -C 4 - R 2和R 3各自独立地为H,(C 1 -C 4 -C 4)烷基,或其中R (C 1 -C 4)烷基,卤素,羟基,(C 1 -C 4)烷基, 烷氧基,氰基,硝基,-NR 5 R 6或-CONR 7 R 13, 8

    Diamino thiazoloindan derivatives and their use
    5.
    发明申请
    Diamino thiazoloindan derivatives and their use 审中-公开
    二氨基噻唑烷衍生物及其用途

    公开(公告)号:US20050197365A1

    公开(公告)日:2005-09-08

    申请号:US11067110

    申请日:2005-02-25

    IPC分类号: A61K31/428 C07D277/84

    摘要: The subject invention provides a compound having the structure: wherein Y is O, NR3R4 or NOR6; R3 is H, alkyl, aralkyl, alkynyl, trifluoroacetyl, t-butoxycarbonyl or an acyl group; R4 is H, alkyl, aralkyl, or alkynyl; R6 is H or C1-C4 alkyl; R1 and R2 are each independently H, alkyl, aralkyl, or alkynyl; the curved line drawn from S to the center of the phenyl ring and the straight line drawn from N to the center of the ring indicate that S and N are part of a 5 membered ring which shares two carbons with the phenyl ring; and the dashed line drawn from the carbon atom on the cyclopentyl ring to Y represents a bond when Y is O or NOR6 and is absent when Y is NR3R4, and wherein wherein X is H or O; and R5 is H, alkyl, trifluoroacetyl, t-butoxycarbonyl or an acyl group, or an enantiomer, or a tautomer, or a pharmaceutically acceptable salt thereof, a process for preparing the compounds and a method of treating Parknison's disease, multiple sclerosis or depression with the compounds of the invention.

    摘要翻译: 本发明提供具有以下结构的化合物:其中Y为O,NR 3 R 4或NOR 6; R 3是H,烷基,芳烷基,炔基,三氟乙酰基,叔丁氧基羰基或酰基; R 4是H,烷基,芳烷基或炔基; R 6是H或C 1 -C 4烷基; R 1和R 2各自独立地为H,烷基,芳烷基或炔基; 从S到苯环中心的曲线和从N到环的中心的直线表示S和N是与苯环共享两个碳的5元环的一部分; 在Y为O或NOR 6时,从环戊基环上的碳原子取代的虚线表示Y,当Y为NR 3 R时,不存在 > 4,并且其中X是H或O; R 5是H,烷基,三氟乙酰基,叔丁氧基羰基或酰基,或其对映体或其互变异构体或其药学上可接受的盐,该化合物的制备方法和 用本发明的化合物治疗帕金森病,多发性硬化或抑郁症。

    Phenylethylamine derivatives
    6.
    发明授权
    Phenylethylamine derivatives 失效
    苯乙胺衍生物

    公开(公告)号:US06251938B1

    公开(公告)日:2001-06-26

    申请号:US09335555

    申请日:1999-06-18

    IPC分类号: A61K3127

    CPC分类号: C07C271/42 C07C271/56

    摘要: This invention is directed to compounds of the following formula: wherein m is from 0-4; X is O or S; Y is halogeno; R1 is hydrogen or C1-4 alkyl; R2 is hydrogen, C1-4 alkyl or optionally substituted propargyl; and R3 and R4 are each independently hydrogen, C1-8 alkyl, C6-12 aryl, C6-12 cycloalkyl or C6-12 aralkyl, R5 is hydrogen or C1-4 alkyl; and pharmaceutically acceptable salts thereof, provided that when X is O, R2 is optionally substituted propargyl. This invention is also directed to the use of these compounds for treating depression, Attention Deficit Disorder (ADD), Attention Deficit and Hyperactivity Disorder (ADHD), Tourette's Syndrome, Alzheimer's Disease and other dementia's such as senile dementia, dementia of the Parkinson's type, vascular dementia and Lewy body dementia. This invention is further directed to a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.

    摘要翻译: 本发明涉及下式的化合物:其中m为0-4; X是O或S; Y为卤素; R1是氢或C1-4烷基; R2是氢,C1-4烷基或任选取代的炔丙基; 并且R 3和R 4各自独立地为氢,C 1-8烷基,C 6-12芳基,C 6-12环烷基或C 6-12芳烷基,R 5为氢或C 1-4烷基; 其中X为O时,R2为任选取代的炔丙基。本发明还涉及这些化合物用于治疗抑郁症,注意力缺陷症(ADD),注意力缺陷和多动症(ADHD)的用途, Tourette综合征,阿尔茨海默病和其他痴呆症如老年性痴呆,帕金森氏型痴呆,血管性痴呆和路易体痴呆。本发明还涉及一种药物组合物,其包含治疗有效量的上述化合物和药学上可接受的 载体