发明授权
- 专利标题： 1-.beta.-methyl-2-thiolic carbapenem derivatives
- 专利标题（中）： 1-β-甲基-2-硫醇碳青霉烯衍生物
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申请号： US155477申请日： 1993-11-19
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公开(公告)号： US5463046A公开(公告)日： 1995-10-31
- 发明人: Jung H. Cho , Chang H. Oh , Ki H. Nam
- 申请人： Jung H. Cho , Chang H. Oh , Ki H. Nam
- 申请人地址： KRX Seoul KRX Seoul
- 专利权人： Dong Kook Pharmaceutical Co., Ltd.,Kwon; Ki-Beom
- 当前专利权人： Dong Kook Pharmaceutical Co., Ltd.,Kwon; Ki-Beom
- 当前专利权人地址： KRX Seoul KRX Seoul
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; A61K31/397 ; A61K31/425 ; A61K31/445 ; A61K31/54 ; A61P31/04 ; C07D477/00 ; C07D477/20 ; C07D487/04
摘要：
The present invention relates to new 1-.beta.-methyl-2-thiolic carbapenem derivatives represented by the following general formula (I) and producing method thereof. ##STR1## The above-mentioned compound is very stable against DHP-1 enzyme due to effective shielding of carbapenem ring structually and is highly effective in both gram-positive and gram-negative microorganism, especially has a remarkable effect on the Pseudomonas aeruginosa known as a disease germ having strong resistance.
公开/授权文献
- USPP7141P Variety of tropical mango named Ed Mitchell 公开/授权日：1990-02-06
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