发明授权
US5468499A Liposomes containing the salt of phosphoramide mustard and related
compounds
失效
含有磷酰胺芥子和相关化合物的盐的脂质体
- 专利标题： Liposomes containing the salt of phosphoramide mustard and related compounds
- 专利标题（中）： 含有磷酰胺芥子和相关化合物的盐的脂质体
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申请号： US152493申请日： 1993-11-15
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公开(公告)号： US5468499A公开(公告)日： 1995-11-21
- 发明人: Kenneth K. Chan , Aeumporn Srigritsanapol
- 申请人： Kenneth K. Chan , Aeumporn Srigritsanapol
- 申请人地址： OH Columbus
- 专利权人： Ohio State University
- 当前专利权人： Ohio State University
- 当前专利权人地址： OH Columbus
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K38/00 ; A61K9/52
摘要：
The present invention provides an anti cancer treatment which has an improved stability and does not produce acrolein. The invention includes dichlorodiethyl phosphoramide drugs including, for example, the cyclohexylamine salt phosphoramide mustard and isophosphoramide mustard and mixtures thereof, which have been entrapped by liposomes. Preferably the liposomes contain sphingomyelin and cholesterol.
公开/授权文献
- US4846991A Novel fatty acid-lactic acid ester 公开/授权日：1989-07-11
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