发明授权
- 专利标题: Gene mapping by hybridization to free chromatin
- 专利标题(中): 通过与游离染色质杂交的基因作图
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申请号: US122141申请日: 1993-09-16
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公开(公告)号: US5470709A公开(公告)日: 1995-11-28
- 发明人: Henry H. Q. Heng , Lap-Chee Tsui
- 申请人: Henry H. Q. Heng , Lap-Chee Tsui
- 申请人地址: CAX Toronto
- 专利权人: HSC Research & Development Ltd. Partnership
- 当前专利权人: HSC Research & Development Ltd. Partnership
- 当前专利权人地址: CAX Toronto
- 优先权: CAX2078377-0 19920916
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
A method is provided for detecting, ordering and mapping genes or DNA sequences in the genome of eukaryotic cells. The method comprises the steps of releasing free chromatin from the nuclei of the cells and contacting the released free chromatin with at least one detectable probe capable of hybridizing to the genes or DNA sequences to be detected, thereby rendering the genes or DNA sequences detectable.
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