Gene mapping by hybridization to free chromatin
    1.
    发明授权
    Gene mapping by hybridization to free chromatin 失效
    通过与游离染色质杂交的基因作图

    公开(公告)号:US5470709A

    公开(公告)日:1995-11-28

    申请号:US122141

    申请日:1993-09-16

    IPC分类号: C12Q1/68

    CPC分类号: C12Q1/6841

    摘要: A method is provided for detecting, ordering and mapping genes or DNA sequences in the genome of eukaryotic cells. The method comprises the steps of releasing free chromatin from the nuclei of the cells and contacting the released free chromatin with at least one detectable probe capable of hybridizing to the genes or DNA sequences to be detected, thereby rendering the genes or DNA sequences detectable.

    摘要翻译: 提供了一种用于检测,排序和映射真核细胞基因组中的基因或DNA序列的方法。 该方法包括以下步骤:从细胞核释放游离染色质,并将释放的游离染色质与能够与要检测的基因或DNA序列杂交的至少一种可检测探针接触,从而使基因或DNA序列可检测。