发明授权
US5474988A 5-phenylpyrrolo-1,4-benzoxazine and 5-phenylpyrrolo-1,4-benzothiazine
compounds, process and intermediates for their production and
pharmaceutical compositions containing them
失效
5-苯基吡咯并-1,4-苯并恶嗪和5-苯基吡咯并-1,4-苯并噻嗪化合物,其制备方法和中间体以及含有它们的药物组合物
- 专利标题: 5-phenylpyrrolo-1,4-benzoxazine and 5-phenylpyrrolo-1,4-benzothiazine compounds, process and intermediates for their production and pharmaceutical compositions containing them
- 专利标题(中): 5-苯基吡咯并-1,4-苯并恶嗪和5-苯基吡咯并-1,4-苯并噻嗪化合物,其制备方法和中间体以及含有它们的药物组合物
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申请号: US196462申请日: 1994-02-15
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公开(公告)号: US5474988A公开(公告)日: 1995-12-12
- 发明人: Patrice Demonchaux , Patrick Lenoir
- 申请人: Patrice Demonchaux , Patrick Lenoir
- 申请人地址: DEX Hanover
- 专利权人: Kali-Chemie Pharma GmbH
- 当前专利权人: Kali-Chemie Pharma GmbH
- 当前专利权人地址: DEX Hanover
- 优先权: DEX4304806.4 19930217
- 主分类号: A61K31/535
- IPC分类号: A61K31/535 ; A61K31/538 ; A61K31/54 ; A61K31/5415 ; A61P29/00 ; A61P37/08 ; C07D265/36 ; C07D279/16 ; C07D498/06 ; C07D513/06 ; C07D265/34 ; C07D279/14
摘要:
Pharmacologically active compounds of formula I ##STR1## which can be substituted in the phenyl rings and in which R.sup.1 denotes hydrogen or lower alkyl,R.sup.2 denotes hydrogen or lower alkyl,Y denotes oxygen or sulfurn represents an integer from 1 to 3Z represents a bond, a CO group or a CH.dbd. group,Q denotes nitrogen or the CH group andR.sup.7, if Q denotes nitrogen, represents an optionally substituted pyridyl or phenyl radical or, if Q denotes the CH group, represents the N-methyl-N-(4-oxo-3H-pyrimidin-2-yl)amino group,and their acid addition salts and processes and intermediates for their preparation.
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