发明授权
US5478956A 8-En-19 11 .beta.-bridged steroids, their production and pharmaceutical
preparations containing them
失效
8-En-19 11β-桥连类固醇,其生产和含有它们的药物制剂
- 专利标题: 8-En-19 11 .beta.-bridged steroids, their production and pharmaceutical preparations containing them
- 专利标题(中): 8-En-19 11β-桥连类固醇,其生产和含有它们的药物制剂
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申请号: US66018申请日: 1993-09-28
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公开(公告)号: US5478956A公开(公告)日: 1995-12-26
- 发明人: Eckhardt Ottow , Gunter Neef , Walter Elger , Martin Schneider , Karl Fritzemeier
- 申请人: Eckhardt Ottow , Gunter Neef , Walter Elger , Martin Schneider , Karl Fritzemeier
- 申请人地址: DEX Berlin
- 专利权人: Schering Aktiengesellschaft
- 当前专利权人: Schering Aktiengesellschaft
- 当前专利权人地址: DEX Berlin
- 优先权: DEX4038128.5 19901127
- 主分类号: A61K31/58
- IPC分类号: A61K31/58 ; A61K31/56 ; A61P5/36 ; A61P13/02 ; A61P15/00 ; A61P15/04 ; A61P25/04 ; A61P35/00 ; C07J20060101 ; C07J53/00 ; C07J63/00 ; C07J71/00 ; C07J73/00
摘要:
8-En-19,11.beta.-bridged steroids of general formula I ##STR1## that have the 8,9-double bond as a new structural feature, and a process for their production are described. The substituents R.sup.1 R.sup.4 -Y, R.sup.4' -Y.sup.', X and Z have the meaning indicated in the description. The new compounds especially have at their disposal pronounced antigestagen effectivenss and are suitable for the production of pharmaceutical preparations.
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