发明授权
US5488132A Process for making optically active alpha-amino ketones and selected novel optically active alpha-amino ketones 失效
制备光学活性α-氨基酮和选择的新型光学活性α-氨基酮的方法

  • 专利标题: Process for making optically active alpha-amino ketones and selected novel optically active alpha-amino ketones
  • 专利标题(中): 制备光学活性α-氨基酮和选择的新型光学活性α-氨基酮的方法
  • 申请号: US232786
    申请日: 1994-04-22
  • 公开(公告)号: US5488132A
    公开(公告)日: 1996-01-30
  • 发明人: John J. Talley
  • 申请人: John J. Talley
  • 申请人地址: MO St. Louis
  • 专利权人: Monsanto Company
  • 当前专利权人: Monsanto Company
  • 当前专利权人地址: MO St. Louis
  • 主分类号: B01J31/24
  • IPC分类号: B01J31/24 C07C231/12 C07C233/47 C07C229/00
Process for making optically active alpha-amino ketones and selected
novel optically active alpha-amino ketones
摘要:
The invention includes selected novel optically active .alpha.-amino ketones which either are themselves useful or are intermediates for the preparation of known ketomethylene pseudopeptides useful as antibiotics, antibiotic enhancers, or enzyme inhibitors. Further, the present invention provides a method for dehydrogenation/asymmetrical hydrogenation to obtain essentially pure antipodes of ketomethylene pseudopeptides having two chiral centers.
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