发明授权
US5493032A Process for the preparation of substituted difluorobenzo-1,3-dioxoles
失效
制备取代的二氟苯-1,3-二氧杂环戊烯的方法
- 专利标题: Process for the preparation of substituted difluorobenzo-1,3-dioxoles
- 专利标题(中): 制备取代的二氟苯-1,3-二氧杂环戊烯的方法
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申请号: US399248申请日: 1995-03-06
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公开(公告)号: US5493032A公开(公告)日: 1996-02-20
- 发明人: Peter Ackermann , Hans-Ruedi Kanel , Bruno Schaub
- 申请人: Peter Ackermann , Hans-Ruedi Kanel , Bruno Schaub
- 申请人地址: NY Tarrytown
- 专利权人: Ciba-Geigy Corporation
- 当前专利权人: Ciba-Geigy Corporation
- 当前专利权人地址: NY Tarrytown
- 优先权: CHX1044/88 19880318; CHX1052/88 19880318
- 主分类号: A61K31/33
- IPC分类号: A61K31/33 ; C07D317/06 ; C07D317/46 ; C07D405/04 ; C07F1/00 ; C07F1/02 ; C07F3/00 ; C07F5/02 ; C07F7/08 ; C07F7/10 ; C07F19/00
摘要:
The reaction of 2,2-difluorobenzo-1,3-dioxole with (a) an alkali metal or an alkali metal compound and then (b) a compound R.sup.1 -Z.sup.1 in which Z.sup.1 is a leaving group, or with an aldehyde produces compounds of formula I ##STR1##
公开/授权文献
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