A hanging folder file box is provided with four substantially equal sides and with two opposite side panels located within the box and having a vertical height less than the vertical height of the sides of the box. The side panels removably receive channels that in turn receive notched ends of hanging folders so that the hanging folders are maintained completely with the box, A lid or cover can be provided to completely cover the hanging folders and their contents. The body of the file holder box is unitary and constructed of a material suitable for folding such as corrugated fiberboard.