发明授权
- 专利标题: Allophanic acid derivatives
- 专利标题(中): 脲基甲酸衍生物
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申请号: US462024申请日: 1995-06-05
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公开(公告)号: US5494922A公开(公告)日: 1996-02-27
- 发明人: George R. Brown , Richard E. Shute
- 申请人: George R. Brown , Richard E. Shute
- 申请人地址: GB2 London
- 专利权人: Zeneca Limited
- 当前专利权人: Zeneca Limited
- 当前专利权人地址: GB2 London
- 优先权: GBX9313269 19930628
- 主分类号: A01N43/40
- IPC分类号: A01N43/40 ; A61K31/44 ; C07C275/54 ; C07D211/26
摘要:
The invention concerns allophanic acid derivatives of formula IR.sup.1 --N(R.sup.2)CO--N(R.sup.3)CO--X.sup.1 --Q--X.sup.2 --GIand pharmaceutically acceptable metabolically labile esters or amides thereof, and pharmaceutically acceptable salts thereof, in which R.sup.1, R.sup.2, R.sup.3, X.sup.1, Q X.sup.2 and G have the meanings given in the specification. The invention also concerns processes for the preparation of the allophanic acid derivatives of formula I, pharmaceutical compositions containing them and their use as inhibitors of the binding of fibrinogen to glycoprotein IIb/IIIa.
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