- 专利标题: Process for the preparation of 1-fluoro-cyclopropane-1-carboxylic acid
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申请号: US404784申请日: 1995-03-15
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公开(公告)号: US5498750A公开(公告)日: 1996-03-12
- 发明人: Stefan Bohm , Albrecht Marhold
- 申请人: Stefan Bohm , Albrecht Marhold
- 申请人地址: DEX Leverkusen
- 专利权人: Bayer Aktiengesellschaft
- 当前专利权人: Bayer Aktiengesellschaft
- 当前专利权人地址: DEX Leverkusen
- 优先权: DEX4131139.6 19910919
- 主分类号: C07C67/42
- IPC分类号: C07C67/42 ; C07C51/09 ; C07C61/15 ; C07C69/74 ; C07C69/753
摘要:
A new process for the preparation of 1-fluoro-cyclopropane-1-carboxylic acid of the formula ##STR1## which process comprises a) reacting in a first step, a 1-fluoro-cyclopropyl phenyl ketone of the formula ##STR2## in which R represents hydrogen, halogen, methyl, methoxy, phenyl or phenoxy, with an peroxy compound in the presence of a diluent, andb) reacting, in a second step, the resulting 1-fluoro-cyclopropane-1-carboxylate of the formula ##STR3## in which R has the abovementioned meaning, with a base in the presence of a diluent, and then acidifying the mixture. New 1-fluoro-cyclopropane-1-carboxylates of the above-mentioned formula.
公开/授权文献
- US4488562A Cigarette making with temperature conditioning 公开/授权日:1984-12-18
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