发明授权
- 专利标题： Thermostable ribonuclease H and genetic constructs therefore
- 专利标题（中）： 因此热稳定性核糖核酸酶H和遗传构建体
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申请号： US465161申请日： 1995-06-05
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公开(公告)号： US5500370A公开(公告)日： 1996-03-19
- 发明人: Jerome J. Jendrisak , Robert E. Smith , Gary A. Dahl
- 申请人： Jerome J. Jendrisak , Robert E. Smith , Gary A. Dahl
- 申请人地址： WI Madison
- 专利权人： Epicentre Technologies
- 当前专利权人： Epicentre Technologies
- 当前专利权人地址： WI Madison
- 主分类号： C12N9/22
- IPC分类号： C12N9/22 ; C12N15/55 ; C12N15/62
摘要：
An essentially pure preparation of thermostable RNase H isolated from Thermus flavus is disclosed. In one preferable form of the invention, the RNase H is capable of biological activity after incubation at temperatures equal to or greater than 70.degree. C. for at least ten minutes. The present invention is also a method of digesting RNA polymers that are in duplex form with a DNA molecule. The method comprises exposing the duplex to the isolated thermostable RNase H. The present invention is also a genetic construct capable of expressing a thermostable RNase H.
公开/授权文献
- US5222182A Optical fiber for laser beam guiding for cure 公开/授权日：1993-06-22
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