发明授权
US5501854A Hybrid reagents capable of selectively releasing molecules into cells
失效
能够选择性地将分子释放到细胞中的混合试剂
- 专利标题： Hybrid reagents capable of selectively releasing molecules into cells
- 专利标题（中）： 能够选择性地将分子释放到细胞中的混合试剂
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申请号： US998754申请日： 1992-12-28
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公开(公告)号： US5501854A公开(公告)日： 1996-03-26
- 发明人: Victor A. Raso
- 申请人： Victor A. Raso
- 申请人地址： MA Boston
- 专利权人： Boston Biomedical Research Institute
- 当前专利权人： Boston Biomedical Research Institute
- 当前专利权人地址： MA Boston
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K16/10 ; C07K16/12 ; C07K16/28 ; C07K16/46 ; C12P21/08 ; A61K39/395 ; A61K39/40
摘要：
Hybrid reagents comprising a first portion having an affinity for a cellular target and a second portion having an affinity for a bioactive molecule are described, said hybrid reagents being capable of selectively releasing the bioactive molecule in response to a change in pH. The hybrid reagents of the present invention can be used diagnostically or therapeutically.
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