发明授权
- 专利标题： Venlafaxine in the treatment of hypothalamic amenorrhea in non-depressed women
- 专利标题（中）： 文拉法辛治疗非抑郁症妇女下丘脑闭经
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申请号： US380903申请日： 1995-01-30
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公开(公告)号： US5506270A公开(公告)日： 1996-04-09
- 发明人: Gertrude V. Upton , Albert T. Derivan , Richard L. Rudolph
- 申请人： Gertrude V. Upton , Albert T. Derivan , Richard L. Rudolph
- 申请人地址： NJ Madison
- 专利权人： American Home Products Corporation
- 当前专利权人： American Home Products Corporation
- 当前专利权人地址： NJ Madison
- 主分类号： A61K31/135
- IPC分类号： A61K31/135 ; A61K31/13 ; A61K31/137 ; A61P13/02 ; A61P15/00 ; A61P43/00 ; A61K31/045 ; A01N31/00
摘要：
This invention provides a method for treating hypothalamic amenorrhea in a non-depressed female mammal by administering to the mammal an effective amount of a hydroxycycloalkanephenethyl amine compound of the following structural formula: ##STR1## in which A is a moiety of the formula ##STR2## wherein the dotted line represents optional unsaturation;R.sub.1 is hydrogen or alkyl;R.sub.2 is alkyl;R.sub.4 is hydrogen, alkyl, formyl, or alkanol;R.sub.5 and R.sub.6 are, independently, hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, dialkylamino, alkanamido, halo, trifluoromethyl, or taken together, methylene dioxy;R.sub.7 is hydrogen or alkyl; andn is 0, 1, 2, 3, or 4;or a pharmaceutically acceptable salt thereof.
公开/授权文献
- US5054678A Furniture clip/tool 公开/授权日：1991-10-08
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