发明授权
- 专利标题: Eliminating internal initiation of soluble CD4 gene
- 专利标题(中): 消除可溶性CD4基因的内部起始
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申请号: US365995申请日: 1994-12-29
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公开(公告)号: US5510256A公开(公告)日: 1996-04-23
- 发明人: Richard J. Kirschner , John E. Mott , Frances M. Eckenrode , David P. Brunner
- 申请人: Richard J. Kirschner , John E. Mott , Frances M. Eckenrode , David P. Brunner
- 申请人地址: MI Kalamazoo
- 专利权人: The Upjohn Company
- 当前专利权人: The Upjohn Company
- 当前专利权人地址: MI Kalamazoo
- 主分类号: C12N1/21
- IPC分类号: C12N1/21 ; A61K38/00 ; C07K14/73 ; C12N15/09 ; C12N15/67 ; C12P21/02 ; C12R1/19 ; C12N15/63 ; C07H21/04 ; C12N5/10
摘要:
The present invention is based upon the discovery that proteins made from genes that include the CD4 sequence in its cDNA can make additional polypeptides as a result of internal translation initiation. This invention is thus directed to DNA sequences which eliminate internal initiation expression in sCD4.
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