发明授权
- 专利标题： pp: A newly identified CD45-associated protein
- 专利标题（中）： pp32：新鉴定的CD45相关蛋白
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申请号： US197793申请日： 1994-02-14
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公开(公告)号： US5510461A公开(公告)日： 1996-04-23
- 发明人: Stefan Meuer , Burkhart Schraven , David Schoenhaut , Sheldon Ratnofsky
- 申请人： Stefan Meuer , Burkhart Schraven , David Schoenhaut , Sheldon Ratnofsky
- 申请人地址： DEX Ludwigshafen
- 专利权人： BASF Aktiengesellschaft
- 当前专利权人： BASF Aktiengesellschaft
- 当前专利权人地址： DEX Ludwigshafen
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/47 ; C12N15/12 ; C12Q1/68 ; C07K1/00 ; C07K14/00 ; C07K16/00
摘要：
This invention relates to a newly identified protein useful for treating diseases of the immune system, methods for obtaining said protein, isolated nucleic acids encoding said protein, and methods for obtaining inhibitors of said protein. The protein of this invention is characterized by an apparent molecular weight of about 32 kD, an isoelectric point of about 4.0-4.5 and coprecipitation with CD45. The protein may also be used in in vitro or in vivo assays to identify inhibitors of T cell activation.
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