发明授权
- 专利标题： Biotinylation reagent and method of use thereof
- 专利标题（中）： 生物素化试剂及其使用方法
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申请号： US295793申请日： 1994-09-14
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公开(公告)号： US5521319A公开(公告)日： 1996-05-28
- 发明人: Erasmus Huber , Bruno Zink , Helmut Lenz , Eva Hoess
- 申请人： Erasmus Huber , Bruno Zink , Helmut Lenz , Eva Hoess
- 专利权人： Huber; Erasmus,Zink; Bruno,Lenz; Helmut,Hoess; Eva
- 当前专利权人： Huber; Erasmus,Zink; Bruno,Lenz; Helmut,Hoess; Eva
- 优先权： DEX4302241.3 19930127
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C07D495/04 ; C07K1/13 ; C07K16/00 ; C12N9/00 ; G01N33/532
摘要：
The invention concerns a compound of the general formula (I): ##STR1## in which Bi denotes a residue derived by cleavage of a carboxyl group from biotin or from a biotin derivative, R.sup.1 and R.sup.2 denote independently of one another hydrogen or C.sub.1 --C.sub.4 alkyl,n denotes an integer from 4 to 10 andX denotes an alkylene residue with a chain length of 5 to 20 atoms substituted by one or several O or/and S atoms and a conjugate of this compound with a substance that has at least one primary or/and secondary amino group NHR.sup.3.