发明授权
US5525596A Absorption enhancer/solubilizer combination for improved bioavailability
of a zwitterionic compound
失效
吸收增强剂/增溶剂组合,用于改善两性离子化合物的生物利用度
- 专利标题: Absorption enhancer/solubilizer combination for improved bioavailability of a zwitterionic compound
- 专利标题(中): 吸收增强剂/增溶剂组合,用于改善两性离子化合物的生物利用度
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申请号: US327081申请日: 1994-10-21
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公开(公告)号: US5525596A公开(公告)日: 1996-06-11
- 发明人: Gerold L. Mosher
- 申请人: Gerold L. Mosher
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; A61K31/715 ; A61K47/18 ; A61K47/40 ; A61K31/205
摘要:
Intestional absorption of zwitterionic compounds is enhanced when the compound is delivered with the absorption enhancer palmitoyl carnitine chloride and the solubilizing agent .beta.-cyclodextrin when compared to delivery with palmitoyl carnitine chloride or .beta.-cyclodextrin alone.
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