发明授权
- 专利标题： 14.alpha., 17.alpha.-ethano-16.alpha.-hydroxy-estratrienes
- 专利标题（中）： 14α，17α-乙酰基-16α-羟基 - 雌三烯
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申请号： US619947申请日： 1990-11-29
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公开(公告)号： US5529993A公开(公告)日： 1996-06-25
- 发明人: Gerald Kirsch , Gunter Neef , Henry Laurent , Rudolf Wiechert , James Bull , Peter Esperling , Walter Elger , Sybille Beier
- 申请人： Gerald Kirsch , Gunter Neef , Henry Laurent , Rudolf Wiechert , James Bull , Peter Esperling , Walter Elger , Sybille Beier
- 申请人地址： DEX Berlin
- 专利权人： Schering Aktiengesellschaft
- 当前专利权人： Schering Aktiengesellschaft
- 当前专利权人地址： DEX Berlin
- 优先权： DEX3939894.3 19891129; DEX3939893.5 19891129; DEX4033871.1 19901022
- 主分类号： A61K31/565
- IPC分类号： A61K31/565 ; A61P5/00 ; C07J1/00 ; C07J53/00
摘要：
A 14.alpha.,17.alpha.-bridged estratriene of formula I ##STR1## wherein (a) OR.sup.3 is in .alpha.-positionR.sup.1, R.sup.2 and R.sup.3, each independently are (i) hydrogen, (ii) ##STR2## in which R.sup.4 is an organic radical with up to 11 carbon atoms or (iii) --(CH.sub.2).sub.n COOH wherein n=1-4, or (iv) R.sup.1 is a benzyl, C.sub.1 -C.sub.8 alkyl or C.sub.3 -C.sub.5 cycloalkyl, or(b) OR.sup.3 is in .beta.-positionR.sup.1, R.sup.2 and R.sup.3, each independently are (i) hydrogen, (ii) an acyl group with 1 to 12 carbon atoms or (iii) R.sup.1 is C.sub.1 -C.sub.8 alkyl, and in both (a) and (b) A--B is an etheno or ethano bridge.
公开/授权文献
- US4077382A Rotary valve for internal combustion engines 公开/授权日：1978-03-07
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