发明授权
- 专利标题： Trypsin inhibitors
- 专利标题（中）： 胰蛋白酶抑制剂
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申请号： US11666申请日： 1993-01-29
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公开(公告)号： US5534498A公开(公告)日： 1996-07-09
- 发明人: Terence K. Brunck , Michael G. Pepe , Daniel A. Pearson , Thomas R. Webb
- 申请人： Terence K. Brunck , Michael G. Pepe , Daniel A. Pearson , Thomas R. Webb
- 申请人地址： CA San Diego
- 专利权人： Corvas International, Inc.
- 当前专利权人： Corvas International, Inc.
- 当前专利权人地址： CA San Diego
- 主分类号： A61K38/55
- IPC分类号： A61K38/55 ; A61P1/00 ; C07C251/76 ; C07C281/10 ; C07K1/113 ; C07K5/072 ; C07K5/078 ; C07K5/093 ; C07K14/81 ; A61K38/00 ; C07K5/06 ; C07K5/08
摘要：
Novel compounds having activity against trypsin are disclosed. Specifically, novel peptide aldehyde analogues that have substantial potency and specificity as inhibitors of mammalian pancreatic trypsin are presented. The compounds are useful in the prevention and treatment of the tissue damage or destruction associated with pancreatitis.
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