发明授权
- 专利标题： Method of preparing nucleotide probes using a bridging complement
- 专利标题（中）： 使用桥连补体制备核苷酸探针的方法
-
申请号： US302332申请日： 1994-09-08
-
公开(公告)号： US5538872A公开(公告)日： 1996-07-23
- 发明人: Chander Bahl , Leopoldo Mendoza , Frank J. McMahon
- 申请人： Chander Bahl , Leopoldo Mendoza , Frank J. McMahon
- 申请人地址： NJ Raritan
- 专利权人： Ortho Diagnostic Systems, Inc.
- 当前专利权人： Ortho Diagnostic Systems, Inc.
- 当前专利权人地址： NJ Raritan
- 主分类号： C07H21/00
- IPC分类号： C07H21/00 ; C12Q1/68 ; C12P19/34 ; C07H21/04
摘要：
The present invention provides labeled nucleotide probes and a procedure for synthesis of the labeled nucleotide probe by a coupling or joinder of two components of the probe, namely a target recognition sequence moiety and a signal generating moiety, through the use of a bridging complement that holds the two moieties in such a position as to allow formation of a sugar-phosphate chemical linkage between the 3' end of one moiety and the 5' end of the other moiety.
公开/授权文献
信息查询
