发明授权
US5548035A Biodegradable copolymer as drug delivery matrix comprising
polyethyleneoxide and aliphatic polyester blocks
失效
包含聚环氧乙烷和脂族聚酯嵌段的药物递送基质的生物可降解共聚物
- 专利标题： Biodegradable copolymer as drug delivery matrix comprising polyethyleneoxide and aliphatic polyester blocks
- 专利标题（中）： 包含聚环氧乙烷和脂族聚酯嵌段的药物递送基质的生物可降解共聚物
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申请号： US238083申请日： 1994-05-04
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公开(公告)号： US5548035A公开(公告)日： 1996-08-20
- 发明人: Ho H. Kim , Guw D. Yeo , Yil W. Yi
- 申请人： Ho H. Kim , Guw D. Yeo , Yil W. Yi
- 申请人地址： KRX Seoul
- 专利权人： Sam Yang Co., Ltd.
- 当前专利权人： Sam Yang Co., Ltd.
- 当前专利权人地址： KRX Seoul
- 优先权： KRX94-270 19940110
- 主分类号： A61K47/30
- IPC分类号： A61K47/30 ; A61K9/20 ; C08G63/00 ; C08G63/06 ; C08G63/66 ; C08G63/664 ; C08G63/78 ; C08G63/91 ; C08G65/32 ; C08G65/332 ; C08G69/40 ; C08G85/00 ; C08L71/02
摘要：
This invention concerns the thermoplastic, biodegradable and nontoxic block copolymer which is easily degraded and excreted in human body by the hydrolysis of intramolecular ester and amide bond. The structure of present copolymer comprises i) hydrophilic and swellable soft domain consisting of polyethyleneoxide(PEO), and ii) hydrophobic, biodegradable, crystallizable and non-swellable hard domain consisting of polylactide(PLA), polyglycolide(PGA), polylactideglycolide(PLdA) and polycaprolactone(PCL).
公开/授权文献
- US4918695A Failure detection for partial write operations for memories 公开/授权日：1990-04-17
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