发明授权
- 专利标题： Long acting GI and esophageal protectant
- 专利标题（中）： 长效GI和食管保护剂
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申请号： US262254申请日： 1994-06-20
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公开(公告)号： US5554379A公开(公告)日： 1996-09-10
- 发明人: Robert Cuca , Keith Lienhop , Thomas Riley , Mitchell I. Kirschner , R. Saul Levinson
- 申请人： Robert Cuca , Keith Lienhop , Thomas Riley , Mitchell I. Kirschner , R. Saul Levinson
- 申请人地址： MO St. Louis
- 专利权人： KV Pharmaceutical Company
- 当前专利权人： KV Pharmaceutical Company
- 当前专利权人地址： MO St. Louis
- 主分类号： A61K9/00
- IPC分类号： A61K9/00 ; A61K9/68 ; A61K47/00
摘要：
A bioadherent, orally ingestible system, which comprises: a water-in-oil system having at least two phases, one phase comprises from about 75% to about 99% by volume of an internal hydrophylic phase and the other phase comprises from about 25% to about l% by volume of an external hydrophobic phase, wherein the external hydrophobic phase comprises two components, one component being about 3% to about 97% by volume of the hydrophobic phase of a hydrophobic oil and the other being about 97% to about 3% of an emulsifier having a HLB value less than about 10.