公开(公告)号：US5554379A

公开(公告)日：1996-09-10

申请号：US262254

申请日：1994-06-20

申请人： Robert Cuca ,  Keith Lienhop ,  Thomas Riley ,  Mitchell I. Kirschner ,  R. Saul Levinson

发明人： Robert Cuca ,  Keith Lienhop ,  Thomas Riley ,  Mitchell I. Kirschner ,  R. Saul Levinson

IPC分类号： A61K9/00 ,  A61K9/68 ,  A61K47/00

CPC分类号： A61K9/006 ,  A61K9/0056 ,  A61K9/0058

摘要： A bioadherent, orally ingestible system, which comprises: a water-in-oil system having at least two phases, one phase comprises from about 75% to about 99% by volume of an internal hydrophylic phase and the other phase comprises from about 25% to about l% by volume of an external hydrophobic phase, wherein the external hydrophobic phase comprises two components, one component being about 3% to about 97% by volume of the hydrophobic phase of a hydrophobic oil and the other being about 97% to about 3% of an emulsifier having a HLB value less than about 10.

摘要翻译： 一种生物相容的口服摄取系统，其包括：具有至少两相的油包水体系，一相包含约75％至约99％体积的内部亲水相，另一相包含约25％ 至约1体积％的外部疏水相，其中外部疏水相包含两种组分，一种组分为疏水相的疏水性油的约3％至约97体积％，另一种为约97％至约 3％的HLB值小于约10的乳化剂。